A functional polymorphism in the 5HTR2C gene associated with stress responses also predicts incident cardiovascular events.

Previously we have shown that a functional nonsynonymous single nucleotide polymorphism (rs6318) of the 5HTR2C gene located on the X-chromosome is associated with hypothalamic-pituitary-adrenal axis response to a stress recall task, and with endophenotypes associated with cardiovascular disease (CVD...

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Auteurs principaux: Beverly H Brummett, Michael A Babyak, Rong Jiang, Svati H Shah, Richard C Becker, Carol Haynes, Megan Chryst-Ladd, Damian M Craig, Elizabeth R Hauser, Ilene C Siegler, Cynthia M Kuhn, Abanish Singh, Redford B Williams
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2013-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC3867393?pdf=render
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