ADAR1 promotes HBV replication through its deaminase domain

Adenosine deaminase acting on RNA1 (ADAR1) is an RNA editing enzyme that modulates the replication of several viruses. Here, we provide evidence showing that ADAR1 stimulates hepatitis B virus (HBV) DNA replication in hepatocellular carcinoma cell lines that are transiently or stably-transfected wit...

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Autores principales: Lin Yuan, Qianying Jia, Shenyong Yang, Nur Fazleen Binti Idris, Yimin Li, Yang Wang, Ya Zhao, Jieli Hu, Yuan Hu, Ailong Huang, Zeng Tu
Formato: Artigo
Lenguaje:Inglês
Publicado: IMR Press 2020-01-01
Colección:Frontiers in Bioscience-Landmark
Materias:
adenosine deaminase
rna1
adar1
hepatitis b virus
rna editing
replication
Acceso en línea:https://www.imrpress.com/journal/FBL/25/4/10.2741/4830
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