Efficient gene editing in Corynebacterium glutamicum using the CRISPR/Cas9 system

Abstract Background Corynebacterium glutamicum (C. glutamicum) has traditionally been used as a microbial cell factory for the industrial production of many amino acids and other industrially important commodities. C. glutamicum has recently been established as a host for recombinant protein express...

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Hlavní autoři: Feng Peng, Xinyue Wang, Yang Sun, Guibin Dong, Yankun Yang, Xiuxia Liu, Zhonghu Bai
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2017-11-01
Edice:Microbial Cell Factories
Témata:
CRISPR/Cas9
Corynebacterium glutamicum
Genome editing
Protein expression
On-line přístup:http://link.springer.com/article/10.1186/s12934-017-0814-6
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