Topical Administration of SLN-Based Gene Therapy for the Treatment of Corneal Inflammation by De Novo IL-10 Production

One of the main challenges in gene therapy is the issue of delivery, and it is especially relevant for the success of gene therapy in the cornea. In the present work, eye drops containing biocompatible non-viral vectors based on solid lipid nanoparticles (SLNs) as gene delivery systems to induce the...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Mónica Vicente-Pascual, Itziar Gómez-Aguado, Julen Rodríguez-Castejón, Alicia Rodríguez-Gascón, Elisabetta Muntoni, Luigi Battaglia, Ana del Pozo-Rodríguez, María Ángeles Solinís Aspiazu
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI AG 2020-06-01
Серии:Pharmaceutics
Предметы:
gene therapy
solid lipid nanoparticles
polyvinyl alcohol (PVA)
corneal inflammation
interleukin-10
transfection
Online-ссылка:https://www.mdpi.com/1999-4923/12/6/584
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы