Flavonolignans from silymarin modulate antibiotic resistance and virulence in Staphylococcus aureus

Antibiotic resistance is currently a serious health problem. Since the discovery of new antibiotics no longer seems to be a sufficient tool in the fight against multidrug-resistant infections, adjuvant (combination) therapy is gaining in importance as well as reducing bacterial virulence. Silymarin...

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Main Authors: Kateřina Holasová, Bára Křížkovská, Lan Hoang, Simona Dobiasová, Jan Lipov, Tomáš Macek, Vladimír Křen, Kateřina Valentová, Tomáš Ruml, Jitka Viktorová
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022-05-01
Serier:Biomedicine & Pharmacotherapy
Fag:
Flavonolignans
Silybin
Silychristin
Multidrug resistance
Staphylococcus aureus
Efflux pump
Online adgang:http://www.sciencedirect.com/science/article/pii/S0753332222001949
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