Correlation of chromosome damage and promoter methylation status of the DNA repair genes MGMT and hMLH1 in Chinese vinyl chloride monomer (VCM)-exposed workers

Objective: To explore the association of the methylation status of MGMT and hMLH1 with chromosome damage induced by vinyl chloride monomer (VCM). Materials and Methods: Methylation of MGMT and hMLH1 was measured in 101 VCM-exposed workers by methylation-specifi c PCR. Chromosome damage in peripheral...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Fen Wu, Jing Liu, Yu-Lan Qiu, Wei Wang, Shou-Min Zhu, Pin Sun, Wen-Bin Miao, Yong-Liang Li, Paul W. Brandt-Rauf, Zhao-Lin Xia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nofer Institute of Occupational Medicine 2013-02-01
Sarja:International Journal of Occupational Medicine and Environmental Health
Aiheet:
vinyl chloride monomer
chromosome damage
MGMT
hMLH1
DNA methylation
Linkit:http://ijomeh.eu/Correlation-of-chromosome-damage-and-promoter-methylation-status-of-the-dna-repair-genes-mgmt-and-hmlh1-in-chinese-vinyl-chloride-monomer-vcm-exposed-workers,2225,0,2.html
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia