Rho-Associated Protein Kinase Inhibitor Treatment Promotes Proliferation and Phagocytosis in Trabecular Meshwork Cells

PurposeContinuous reductions in trabecular meshwork (TM) cellularity inhibit aqueous humor (AH) outflow, which is the main cause of primary open-angle glaucoma. Rho-associated protein kinase inhibitor (ROCKi) targets the TM to reduce intraocular pressure (IOP) and increase AH outflow facility. Howev...

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Главные авторы: Wenshi Chen, Xuejiao Yang, Jingwang Fang, Yuqing Zhang, Wei Zhu, Xian Yang
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020-03-01
Серии:Frontiers in Pharmacology
Предметы:
Rho-associated protein kinase inhibitor
glaucoma
trabecular meshwork
proliferation
phagocytosis
Online-ссылка:https://www.frontiersin.org/article/10.3389/fphar.2020.00302/full
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