Rho-Associated Protein Kinase Inhibitor Treatment Promotes Proliferation and Phagocytosis in Trabecular Meshwork Cells

PurposeContinuous reductions in trabecular meshwork (TM) cellularity inhibit aqueous humor (AH) outflow, which is the main cause of primary open-angle glaucoma. Rho-associated protein kinase inhibitor (ROCKi) targets the TM to reduce intraocular pressure (IOP) and increase AH outflow facility. Howev...

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Main Authors: Wenshi Chen, Xuejiao Yang, Jingwang Fang, Yuqing Zhang, Wei Zhu, Xian Yang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Assuntos:
Rho-associated protein kinase inhibitor
glaucoma
trabecular meshwork
proliferation
phagocytosis
Acceso en liña:https://www.frontiersin.org/article/10.3389/fphar.2020.00302/full
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