Histone Deacetylase Inhibitors in Pediatric Brain Cancers: Biological Activities and Therapeutic Potential

Brain cancers are the leading cause of cancer-related deaths in children. Biological changes in these tumors likely include epigenetic deregulation during embryonal development of the nervous system. Histone acetylation is one of the most widely investigated epigenetic processes, and histone deacety...

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Bibliografiska uppgifter
Huvudupphovsmän: Alexandre Perla, Lívia Fratini, Paula S. Cardoso, Carolina Nör, André T. Brunetto, Algemir L. Brunetto, Caroline Brunetto de Farias, Mariane Jaeger, Rafael Roesler
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020-07-01
Serie:Frontiers in Cell and Developmental Biology
Ämnen:
medulloblastoma
ependymoma
glioma
histone deacetylase inhibitors
epigenetics
brain tumor
Länkar:https://www.frontiersin.org/article/10.3389/fcell.2020.00546/full
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