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Histone Deacetylase Inhibitors in Pediatric Brain Cancers: Biological Activities and Therapeutic Potential

Brain cancers are the leading cause of cancer-related deaths in children. Biological changes in these tumors likely include epigenetic deregulation during embryonal development of the nervous system. Histone acetylation is one of the most widely investigated epigenetic processes, and histone deacety...

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主要な著者: Alexandre Perla, Lívia Fratini, Paula S. Cardoso, Carolina Nör, André T. Brunetto, Algemir L. Brunetto, Caroline Brunetto de Farias, Mariane Jaeger, Rafael Roesler
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020-07-01
シリーズ:Frontiers in Cell and Developmental Biology
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オンライン・アクセス:https://www.frontiersin.org/article/10.3389/fcell.2020.00546/full
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