New Morphiceptin Peptidomimetic Incorporating (1<i>S</i>,2<i>R</i>,3<i>S</i>,4<i>S</i>,5<i>R</i>)-2-Amino-3,4,5-trihydroxycyclopen-tane-1-carboxylic Acid: Synthesis and Structural Study

We present the synthesis and structural study of a new peptidomimetic of morphiceptin, which can formally be considered as the result of the replacement of the central proline residue of this natural analgesic drug with a subunit of (1<i>S</i>,2<i>R</i>,3<i>S</i>,...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Raquel Soengas, Marcos Lorca, Begoña Pampín, Víctor M. Sánchez-Pedregal, Ramón J. Estévez, Juan C. Estévez
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2020-06-01
Saila:Molecules
Gaiak:
morphiceptin
alicyclic β-amino acids
peptidomimetics
nitro sugars
analgesic
Sarrera elektronikoa:https://www.mdpi.com/1420-3049/25/11/2574
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