Autophagy, a novel pathway to regulate calcium mobilization in T lymphocytes

The T lymphocyte response initiates with the recognition of MHC/peptides on antigen presenting cells by the T cell receptor (TCR). After the TCR engagement, the proximal signaling pathways are activated for downstream cellular events. Among these pathways, the calcium signaling flux is activated thr...

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Autores principales: Wei eJia, Mingxiao eHe, You-Wen eHe, Ian eMcleod
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2013-07-01
Colección:Frontiers in Immunology
Materias:
Autophagy
T lymphocytes
Calcium flux
ER homeostasis
ER-phagy
Acceso en línea:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00179/full
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