Engineering ROS‐Responsive Bioscaffolds for Disrupting Myeloid Cell‐Driven Immunosuppressive Niche to Enhance PD‐L1 Blockade‐Based Postablative Immunotherapy

Abstract The existence of inadequate ablation remains an important cause of treatment failure for loco‐regional ablation therapies. Here, using a preclinical model, it is reported that inadequate microwave ablation (iMWA) induces immunosuppressive niche predominated by myeloid cells. The gene signat...

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Detaylı Bibliyografya
Asıl Yazarlar: Shaoyue Li, Chunyan Zhu, Xianli Zhou, Liang Chen, Xiaowan Bo, Yuting Shen, Xin Guan, Xiaoxia Han, Dandan Shan, Liping Sun, Yu Chen, Huixiong Xu, Wenwen Yue
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley 2022-04-01
Seri Bilgileri:Advanced Science
Konular:
checkpoint blockade
immunotherapy
myeloid cells
nanomedicine
tumor therapy
Online Erişim:https://doi.org/10.1002/advs.202104619
Etiketler: Etiketle
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