Engineering ROS‐Responsive Bioscaffolds for Disrupting Myeloid Cell‐Driven Immunosuppressive Niche to Enhance PD‐L1 Blockade‐Based Postablative Immunotherapy

Abstract The existence of inadequate ablation remains an important cause of treatment failure for loco‐regional ablation therapies. Here, using a preclinical model, it is reported that inadequate microwave ablation (iMWA) induces immunosuppressive niche predominated by myeloid cells. The gene signat...

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Bibliografiska uppgifter
Huvudupphovsmän: Shaoyue Li, Chunyan Zhu, Xianli Zhou, Liang Chen, Xiaowan Bo, Yuting Shen, Xin Guan, Xiaoxia Han, Dandan Shan, Liping Sun, Yu Chen, Huixiong Xu, Wenwen Yue
Materialtyp: Artigo
Språk:Inglês
Publicerad: Wiley 2022-04-01
Serie:Advanced Science
Ämnen:
checkpoint blockade
immunotherapy
myeloid cells
nanomedicine
tumor therapy
Länkar:https://doi.org/10.1002/advs.202104619
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