PLGA Microspheres Loaded with β-Cyclodextrin Complexes of Epigallocatechin-3-Gallate for the Anti-Inflammatory Properties in Activated Microglial Cells

Although epigallocatechin-3-gallate (EG) is well-known as a potent antioxidant and free radical scavenger for neurodegenerative diseases, it still has disadvantages that reduce its treatment effectiveness due to low bioavailability, slow absorption, and water solubility. Therefore, the aim of this s...

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Main Authors: Chun-Yuan Cheng, Quoc-Hue Pho, Xiao-Yu Wu, Ting-Yu Chin, Chien-Min Chen, Peng-Hsiang Fang, Yung-Chang Lin, Ming-Fa Hsieh
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2018-05-01
Serija:Polymers
Teme:
microglia cells
epigallocatechin-3-gallate
PLGA
non-toxicity
biodegradable
anti-inflammation
bovine serum albumin
β-cyclodextrin
Online dostop:http://www.mdpi.com/2073-4360/10/5/519
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