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Inhibition of RNA polymerase III transcription by Triptolide attenuates colorectal tumorigenesis
Abstract Background Upregulation of RNA polymerase (Pol) III products, including tRNAs and 5S rRNA, in tumor cells leads to enhanced protein synthesis and tumor formation, making it a potential target for cancer treatment. In this study, we evaluated the inhibition of Pol III transcription by tripto...
שמור ב:
| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BMC
2019-05-01
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| סדרה: | Journal of Experimental & Clinical Cancer Research |
| נושאים: | |
| גישה מקוונת: | http://link.springer.com/article/10.1186/s13046-019-1232-x |
| תגים: |
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