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The Natural Product Andrographolide Ameliorates Calcific Aortic Valve Disease by Regulating the Proliferation of Valve Interstitial Cells via the MAPK-ERK Pathway

Calcific aortic valve disease (CAVD) is an active pathobiological process that involves fibrosis and calcification of aortic valve leaflets, thereby causing cardiac hemodynamic changes and eventually heart failure. Cell proliferation changes at the initial stage of CAVD are an important target for p...

詳細記述

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書誌詳細
主要な著者: Yuming Huang, Ming Liu, Chungeng Liu, Nianguo Dong, Liang Chen
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2022-04-01
シリーズ:Frontiers in Pharmacology
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オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fphar.2022.871748/full
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