Oxygen Desaturation Is Associated With Fibrocyte Activation via Epidermal Growth Factor Receptor/Hypoxia-Inducible Factor-1α Axis in Chronic Obstructive Pulmonary Disease

Fibrocytes are bloodborne mesenchymal progenitors which accumulate and differentiate at the disease site. We investigated whether hypoxemia activates fibrocytes, accelerating airflow limitation and exercise intolerance in chronic obstructive pulmonary disease (COPD) patients. Flow cytometry was used...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Chun-Hua Wang, Chun-Yu Lo, Hung-Yu Huang, Tsai-Yu Wang, Chih-Ming Weng, Chih-Jung Chen, Yu-Chen Huang, Fu-Tsai Chung, Chang-Wei Lin, Kian Fan Chung, Han-Pin Kuo
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2022-05-01
Serija:Frontiers in Immunology
Teme:
chronic obstructive pulmonary disease (COPD)
fibrocyte
epidermal growth factor receptor (EGFR)
hypoxia-inducible factor-1α (HIF-1α)
desaturation
Online pristup:https://www.frontiersin.org/articles/10.3389/fimmu.2022.852713/full
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items