Studying polymorphic variants of the NAT2 gene (NAT2*5 and NAT2*7) in Nenets populations of Northern Siberia

Abstract Background N-acetyltransferase 2 plays a crucial role in the metabolism of a wide range of xenobiotics, including many drugs, carcinogens, and other chemicals in the human environment. The article presents for the first time data on the frequency of two important “slow” variants of NAT2 gen...

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Bibliografiska uppgifter
Huvudupphovsmän: Roza Pavlovna Tiis, Ludmila Pavlovna Osipova, Daria Veniaminovna Lichman, Elena Nikolaevna Voronina, Maxim Leonidovich Filipenko
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMC 2020-10-01
Serie:BMC Genetics
Ämnen:
Xenobiotics
NAT2 gene
NAT2*5, rs1801280
NAT2*7, rs1799931
Forest and Tundra Nenets
Northern Siberia
Länkar:http://link.springer.com/article/10.1186/s12863-020-00909-4
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