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Epigenetic Regulation of Host Defense Peptide Synthesis: Synergy Between Histone Deacetylase Inhibitors and DNA/Histone Methyltransferase Inhibitors
Host defense peptides (HDPs) are an integral part of the innate immune system acting as the first line of defense. Modulation of HDP synthesis has emerged as a promising host-directed approach to fight against infections. Inhibition of histone deacetylation or DNA methylation is known to enhance HDP...
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Hoofdauteurs: | , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
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Frontiers Media S.A.
2022-04-01
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Reeks: | Frontiers in Immunology |
Onderwerpen: | |
Online toegang: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.874706/full |
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