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Impaired macrophage and satellite cell infiltration occurs in a muscle-specific fashion following injury in diabetic skeletal muscle.

Systemic elevations in PAI-1 suppress the fibrinolytic pathway leading to poor collagen remodelling and delayed regeneration of tibialis anterior (TA) muscles in type-1 diabetic Akita mice. However, how impaired collagen remodelling was specifically attenuating regeneration in Akita mice remained un...

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Autori principali: Matthew P Krause, Dhuha Al-Sajee, Donna M D'Souza, Irena A Rebalka, Jasmin Moradi, Michael C Riddell, Thomas J Hawke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3741394?pdf=render
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