Chemokines as a Conductor of Bone Marrow Microenvironment in Chronic Myeloid Leukemia

All blood lineage cells are generated from hematopoietic stem cells (HSCs), which reside in bone marrow after birth. HSCs self-renew, proliferate, and differentiate into mature progeny under the control of local microenvironments including hematopoietic niche, which can deliver regulatory signals in...

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Bibliographische Detailangaben
Hauptverfasser: Naofumi Mukaida, Yamato Tanabe, Tomohisa Baba
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2017-08-01
Schriftenreihe:International Journal of Molecular Sciences
Schlagworte:
CCL3
CXCL12
CXCR4
hematopoietic stem cell
hematopoietic progenitor cell
leukemia stem cell
niche
Online Zugang:https://www.mdpi.com/1422-0067/18/8/1824
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