Pan-Cancer Single-Cell Analysis Reveals the Core Factors and Pathway in Specific Cancer Stem Cells of Upper Gastrointestinal Cancer

Upper gastrointestinal cancer (UGIC) is an aggressive carcinoma with increasing incidence and poor outcomes worldwide. Here, we collected 39,057 cells, and they were annotated into nine cell types. By clustering cancer stem cells (CSCs), we discovered the ubiquitous existence of sub-cluster CSCs in...

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Hlavní autoři: Leijie Li, Yujia Zhang, Yongyong Ren, Zhiwei Cheng, Yuening Zhang, Xinbo Wang, Hongyu Zhao, Hui Lu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-05-01
Edice:Frontiers in Bioengineering and Biotechnology
Témata:
upper gastrointestinal cancers
cancer stem cell
single-cell sequence data
pan-cancer analysis
oncogene
On-line přístup:https://www.frontiersin.org/articles/10.3389/fbioe.2022.849798/full
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