On the interchangeability of calcineurine inhibitors

Calcineurin inhibitors, cyclosporine and tacrolimus, are the main immunosuppressants used in solid organ transplantation, but the peculiarities of their pharmacokinetics allow to classify them to a group of medicines with a narrow therapeutic range. Currently in Russia more than 10 generic drugs of...

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Bibliographische Detailangaben
Hauptverfasser: K. E. Zatolochina, R. N. Alyautdin, E. O. Zhuravleva, E. Yu. Pasternak, M. A. Darmostukova, E. Yu. Kolesnikova, B. K. Romanov
Format: Artigo
Sprache:Russo
Veröffentlicht: Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation 2018-02-01
Schriftenreihe:Безопасность и риск фармакотерапии
Schlagworte:
ингибиторы кальциневрина
циклоспорин
такролимус
биоэквивалентность
взаимозаменяемость
calcineurine inhibitors
cyclosporine
tacrolimus
bioequivalence
interchangeability
Online Zugang:https://www.risksafety.ru/jour/article/view/41
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