SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology

Summary: VPS10P domain receptors emerge as central regulators of intracellular protein sorting in neurons with relevance for various brain pathologies. Here, we identified a role for the family member SorCS2 in protection of neurons from oxidative stress and epilepsy-induced cell death. We show that...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Anna R. Malik, Kinga Szydlowska, Karolina Nizinska, Antonino Asaro, Erwin A. van Vliet, Oliver Popp, Gunnar Dittmar, Raphaela Fritsche-Guenther, Jennifer A. Kirwan, Anders Nykjaer, Katarzyna Lukasiuk, Eleonora Aronica, Thomas E. Willnow
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2019-03-01
Sraith:Cell Reports
Rochtain Ar Líne:http://www.sciencedirect.com/science/article/pii/S2211124719301986
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla