Immediate effects of maternal deprivation on the (re)activity of the HPA axis differ in CD1 and C57Bl/6J mouse pups

The postnatal development of the mouse is characterised by a period of hypo-responsiveness of the hypothalamic-pituitary-adrenal (HPA) axis to mild stressors. Maternal deprivation (MD) during this period can disrupt the quiescence of the HPA-axis. The present study examined the influence of strain (...

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Autors principals: Nikolaos P Daskalakis, Leo eEnthoven, Edwige eSchoonheere, Edo Ronald De Kloet, Melly S Oitzl
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014-11-01
Col·lecció:Frontiers in Endocrinology
Matèries:
Corticosterone
Maternal Deprivation
ACTH
genetic
CRH
Hypothalamic-Pituitary-Adrenal Axis
Accés en línia:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00190/full
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