Effect of Aggregated β-Amyloid (1-42) on Synaptic Plasticity of Hippocampal Dentate Gyrus Granule Cells in Vivo

Introduction: Alzheimer’s disease (AD) is a common neurodegenerative disorder in elderly people with an impairment of cognitive decline and memory loss. β-amyloid (Aβ) as a potent neurotoxic peptide has a pivotal role in the pathogenesis of AD. This disease begins with impairment in synaptic functio...

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Hlavní autoři: Shirin Babri, Mohammad Amani, Gisou Mohaddes, Alireza Alihemmati, Hadi Ebrahimi
Médium: Artigo
Jazyk:Inglês
Vydáno: Tabriz University of Medical Sciences 2012-12-01
Edice:BioImpacts
Témata:
β-Amyloid
Synaptic Plasticity
Dentate Gyrus
Long-Term Potentiation
Beta-Amyloid
On-line přístup:http://dx.doi.org/10.5681/bi.2012.022
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