Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells.

Pancreatic β-cells synthesize and release serotonin (5 hydroxytryptamine, 5HT); however, the role of 5HT receptors on glucose stimulated insulin secretion (GSIS) and the mechanisms mediating this function is not fully understood. The aims of this study were to determine the expression profile of 5HT...

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Main Authors: Luis Rodrigo Cataldo, María L Mizgier, Roberto Bravo Sagua, Fabián Jaña, César Cárdenas, Paola Llanos, Dolores Busso, Pablo Olmos, José E Galgani, José L Santos, Víctor A Cortés
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC5271329?pdf=render
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