Hedgehog proteins and parathyroid hormone‐related protein are involved in intervertebral disc maturation, degeneration, and calcification

Abstract Parathyroid hormone‐related protein (PTHrP) and hedgehog signaling play an important role in chondrocyte development, (hypertrophic) differentiation, and/or calcification, but their role in intervertebral disc (IVD) degeneration is unknown. Better understanding their involvement may provide...

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Bibliographic Details
Main Authors: Frances C. Bach, Kim M. deRooij, Frank M. Riemers, Joseph W. Snuggs, Willem A. M. deJong, Ying Zhang, Laura B. Creemers, Danny Chan, Christine Le Maitre, Marianna A. Tryfonidou
Format: Artigo
Language:Inglês
Published: Wiley 2019-12-01
Series:JOR Spine
Subjects:
calcification
IHH
IVD
PTHrP
SHH
Online Access:https://doi.org/10.1002/jsp2.1071
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