Intranasal immunization with nontypeable Haemophilus influenzae outer membrane vesicles induces cross-protective immunity in mice.

Haemophilus influenzae is a Gram-negative human-restricted bacterium that can act as a commensal and a pathogen of the respiratory tract. Especially nontypeable H. influenzae (NTHi) is a major threat to public health and is responsible for several infectious diseases in humans, such as pneumonia, si...

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Main Authors: Sandro Roier, Deborah R Leitner, Jeremy Iwashkiw, Kristina Schild-Prüfert, Mario F Feldman, Georg Krohne, Joachim Reidl, Stefan Schild
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3411803?pdf=render
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