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Zebrafish-based identification of the antiseizure nucleoside inosine from the marine diatom Skeletonema marinoi.

With the goal of identifying neuroactive secondary metabolites from microalgae, a microscale in vivo zebrafish bioassay for antiseizure activity was used to evaluate bioactivities of the diatom Skeletonema marinoi, which was recently revealed as being a promising source of drug-like small molecules....

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Autori principali: Théo Brillatz, Chiara Lauritano, Maxime Jacmin, Supitcha Khamma, Laurence Marcourt, Davide Righi, Giovanna Romano, Francesco Esposito, Adrianna Ianora, Emerson F Queiroz, Jean-Luc Wolfender, Alexander D Crawford
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2018-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC5916873?pdf=render
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