Porcine circovirus type 2 upregulates endothelial-derived IL-8 production in porcine iliac artery endothelial cells via the RIG-I/MDA-5/MAVS/JNK signaling pathway

Abstract Background Dysfunction of endothelial cells and vascular system is one of the most important pathological changes of porcine circovirus disease (PCVD) caused by porcine circovirus type 2 (PCV2). PCV2-infected endothelial cells can upregulate the production of endothelial-derived IL-8, which...

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Main Authors: Fengyang Shi, Qiuming Li, Shiyu Liu, Fengying Liu, Jianfang Wang, Defeng Cui, Xiaolin Hou, Shuanghai Zhou, Yonghong Zhang, Huanrong Li
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-07-01
Serier:BMC Veterinary Research
Fag:
Porcine circovirus type 2
Endothelium-derived IL-8
Porcine iliac artery endothelial cells
RIG-I-like signaling pathway
JNK signaling pathway
Online adgang:http://link.springer.com/article/10.1186/s12917-020-02486-1
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