xperimental Evaluation of the Possibility of using the LAL test to Determine Bacterial Endotoxins in Vaccines for Rabies Prophylaxis

Relevance. The presence of pyrogenic impurities in finished dosage forms of concentrated cultural anti-rabies vaccines produced in the Russian Federation is determined using pyrogenicity tests on rabbits (in vivo). In accordance with the decision of the Board of the Eurasian Economic Commission date...

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Main Authors: A. V. Muhacheva, O. A. Barkhaleva, O. V. Shapovalova, N. P. Neugodova, A. Yu. Butirskiy, A. A. Movsesyants, R. A. Volkova, K. A. Sarkisyan
Format: Artigo
Sprog:Russo
Udgivet: Numikom LLC 2021-11-01
Serier:Эпидемиология и вакцинопрофилактика
Fag:
lal test
bacterial endotoxins in vaccines
rabies vaccine tests
gel-clot test
turbidimetric kinetic test
chromogenic kinetic test
Online adgang:https://www.epidemvac.ru/jour/article/view/1371
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