Development of Novel, Potent Phosphatidyl–Choline-Specific Phospholipase C Inhibitors

The phosphatidyl−choline-specific phospholipase C (PC-PLC) enzyme has been shown to be an important enzyme involved in various cell-signaling processes. Furthermore, PC-PLC has been shown to be upregulated in various cancer cell lines, thereby presenting itself as a potential anti-cancer t...

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Main Authors: Lisa I. Pilkington, Euphemia Leung, David Barker
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2019-08-01
Series:Proceedings
Assuntos:
PC-PLC
SAR study
enzyme inhibition
phospholipase C
Acceso en liña:https://www.mdpi.com/2504-3900/22/1/67
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