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Pathophysiology of Motor Dysfunction in Parkinson’s Disease as the Rationale for Drug Treatment and Rehabilitation

Cardinal motor features of Parkinson’s disease (PD) include bradykinesia, rest tremor, and rigidity, which appear in the early stages of the disease and largely depend on dopaminergic nigrostriatal denervation. Intermediate and advanced PD stages are characterized by motor fluctuations and dyskinesi...

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主要な著者: Francesca Magrinelli, Alessandro Picelli, Pierluigi Tocco, Angela Federico, Laura Roncari, Nicola Smania, Giampietro Zanette, Stefano Tamburin
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Limited 2016-01-01
シリーズ:Parkinson's Disease
オンライン・アクセス:http://dx.doi.org/10.1155/2016/9832839
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