Transcriptome analysis of signaling pathways of human peritoneal mesothelial cells in response to different osmotic agents in a peritoneal dialysis solution

Abstract Background Glucose is a primary osmotic agent in peritoneal dialysis (PD) solutions, but its long-term use causes structural alteration of the peritoneal membrane (PM). Hyperbranched polyglycerol (HPG) is a promising alternative to glucose. This study was designed to compare the cellular re...

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Hlavní autoři: Bin Liu, Shijian Feng, Ghida Dairi, Qiunong Guan, Irina Chafeeva, Hao Wang, Richard Liggins, Gerald da Roza, Jayachandran N. Kizhakkedathu, Caigan Du
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2019-05-01
Edice:BMC Nephrology
Témata:
Osmotic agents
Hyperbranched polyglycerol
Glucose
Transcriptome
Signaling pathways
Peritoneal mesothelial cells
On-line přístup:http://link.springer.com/article/10.1186/s12882-019-1376-0
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