Inhibition of growth of colorectal cancer patient-derived subcutaneous xenografts using combined Wnt signaling pathway inhibitor and 5‑fluorouracil

Purpose of the study. Was to analyze antitumor efficacy of the XAV 939 Wnt signaling pathway inhibitor and its combination with 5 fluorouracil in subcutaneous xenografts derived from patients with colorectal cancer.Materials and methods. Antitumor efficacy of the agents and their combination was stu...

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Main Authors: A. S. Goncharova, A. V. Galina, D. V. Khodakova, G. Yu. Egorov, A. Yu. Maksimov, E. N. Kolesnikov, E. F. Komarova, A. A. Kiblitskaya, E. V. Zaikina, L. Z. Kurbanova, M. V. Mindar
Format: Artigo
Jezik:Russo
Izdano: QUASAR, LLC 2022-03-01
Serija:Issledovaniâ i Praktika v Medicine
Teme:
colorectal cancer
xenograft
murine models
in vivo studies
wnt signaling pathway
wnt inhibitor
Online dostop:https://www.rpmj.ru/rpmj/article/view/746
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