[D-Ala2, D-Leu5] Enkephalin Attenuates Hepatic Ischemia–Reperfusion Injury in Cirrhotic Rats

Background and AimsHepatic ischemia–reperfusion injury (IRI) is a common phenomenon that occurs after liver transplantation and liver tumor surgery. It can cause liver dysfunction and recovery failure after liver surgery, even leading to acute liver failure. Our aim is to investigate the protective...

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Bibliographic Details
Main Authors: Jueying Liu, Yuan Wang, Qianling Pan, Xueqing Chen, Yifeng Qu, Hao Zhu, Li Zheng, Yinghui Fan
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Surgery
Subjects:
hepatic ischemia–reperfusion injury
delta opioid receptor
phosphatidylinositol-3-kinase (PI3K)/Akt pathway
cirrhotic livers
rats
DADLE
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2022.839296/full
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