Congenital Aneuploidy in Klinefelter Syndrome with B-Cell Acute Lymphoblastic Leukemia Might Be Associated with Chromosomal Instability and Reduced Telomere Length

Rare congenital aneuploid conditions such as trisomy 13, trisomy 18, trisomy 21 and Klinefelter syndrome (KS, 47,XXY) are associated with higher susceptibility to developing cancer compared with euploid genomes. Aneuploidy frequently co-exists with chromosomal instability, which can be viewed as a “...

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Bibliografische gegevens
Hoofdauteur: Eigil Kjeldsen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2022-05-01
Reeks:Cancers
Onderwerpen:
Klinefelter syndrome
chromosomal instability
telomere length
hematological malignancy
iQ-FISH
Online toegang:https://www.mdpi.com/2072-6694/14/9/2316
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