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Congenital Aneuploidy in Klinefelter Syndrome with B-Cell Acute Lymphoblastic Leukemia Might Be Associated with Chromosomal Instability and Reduced Telomere Length

Rare congenital aneuploid conditions such as trisomy 13, trisomy 18, trisomy 21 and Klinefelter syndrome (KS, 47,XXY) are associated with higher susceptibility to developing cancer compared with euploid genomes. Aneuploidy frequently co-exists with chromosomal instability, which can be viewed as a “...

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Bibliografiske detaljer
Hovedforfatter: Eigil Kjeldsen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-05-01
Serier:Cancers
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Online adgang:https://www.mdpi.com/2072-6694/14/9/2316
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