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Neuropathogenesis of Zika Virus in a Highly Susceptible Immunocompetent Mouse Model after Antibody Blockade of Type I Interferon.
Animal models are needed to better understand the pathogenic mechanisms of Zika virus (ZIKV) and to evaluate candidate medical countermeasures. Adult mice infected with ZIKV develop a transient viremia, but do not demonstrate signs of morbidity or mortality. Mice deficient in type I or a combination...
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Main Authors: | , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Public Library of Science (PLoS)
2017-01-01
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Series: | PLoS Neglected Tropical Diseases |
Acceso en liña: | http://europepmc.org/articles/PMC5249252?pdf=render |
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