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Efficient, chemoselective synthesis of immunomicelles using single-domain antibodies with a C-terminal thioester
<p>Abstract</p> <p>Background</p> <p>Classical bioconjugation strategies for generating antibody-functionalized nanoparticles are non-specific and typically result in heterogeneous compounds that can be compromised in activity. Expression systems based on self-cleavable...
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Main Authors: | , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
BMC
2009-07-01
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Series: | BMC Biotechnology |
Online Access: | http://www.biomedcentral.com/1472-6750/9/66 |
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