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KMT5A-methylated SNIP1 promotes triple-negative breast cancer metastasis by activating YAP signaling
SNIP1 methylation initiates its oncogenic functions. Here, the authors show that SNIP1 is methylated by KMT5A and this leads to downstream signalling that activates the YAP pathway, resulting in tumorigenesis and metastasis.
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Portfolio
2022-04-01
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| シリーズ: | Nature Communications |
| オンライン･アクセス: | https://doi.org/10.1038/s41467-022-29899-w |
| タグ: |
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