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KMT5A-methylated SNIP1 promotes triple-negative breast cancer metastasis by activating YAP signaling
SNIP1 methylation initiates its oncogenic functions. Here, the authors show that SNIP1 is methylated by KMT5A and this leads to downstream signalling that activates the YAP pathway, resulting in tumorigenesis and metastasis.
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Portfolio
2022-04-01
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| Collection: | Nature Communications |
| Accès en ligne: | https://doi.org/10.1038/s41467-022-29899-w |
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