Heparanase Levels Are Elevated in the Plasma of Pediatric Cancer Patients and Correlate with Response to Anticancer Treatment

Heparanase is an endoglycosidase that specifically cleaves heparan sulfate (HS) side chains of heparan sulfate proteoglycans, the major proteoglycan in the extracellular matrix (ECM) and cell surfaces. Heparanase upregulation was documented in an increasing number of primary human tumors, correlatin...

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Autori principali: Itay Shafat, Ayelet Ben Barak, Sergey Postovsky, Ronit Elhasid, Neta Ilan, Israel Vlodavsky, Miriam Weyl Ben Arush
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2007-11-01
Serie:Neoplasia: An International Journal for Oncology Research
Soggetti:
Heparanase
ELISA
marker
anticancer treatment
Accesso online:http://www.sciencedirect.com/science/article/pii/S1476558607800194
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