Assessment of viral methylation levels for high risk HPV types by newly designed consensus primers PCR and pyrosequencing.

Measuring viral DNA methylation in human papillomavirus (HPV) infected women showed promise for accurate detection of high-grade cervical lesions and cancer. Methylation status has been widely investigated for HPV16, sporadically for other HPV types.Objective of this methodological study was to set...

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Autori principali: Anna Gillio-Tos, Valentina Fiano, Chiara Grasso, Morena Trevisan, Silvia Gori, Alessandra Mongia, Laura De Marco, Guglielmo Ronco, New Technologies for Cervical Cancer Screening (NTCC) Working Group
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2018-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC5868804?pdf=render
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