Carboxypeptidase E-∆N Promotes Proliferation and Invasion of Pancreatic Cancer Cells via Upregulation of CXCR2 Gene Expression

Pancreatic cancer is one of the leading causes of cancer-related mortality worldwide. The molecular basis for the pathogenesis of this disease remains elusive. In this study, we have investigated the role of wild-type Carboxypeptidase E (CPE-WT) and a 40 kDa N-terminal truncated isoform, CPE-&#9...

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Hlavní autoři: Sangeetha Hareendran, Xuyu Yang, Hong Lou, Lan Xiao, Y. Peng Loh
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2019-11-01
Edice:International Journal of Molecular Sciences
Témata:
carboxypeptidase e
pancreatic cancer
cell proliferation
cell invasion
On-line přístup:https://www.mdpi.com/1422-0067/20/22/5725
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