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Imepitoin Shows Benzodiazepine-Like Effects in Models of Anxiety

Imepitoin is a low affinity partial agonist for the benzodiazepine binding site of γ-aminobutyric acid (GABAA) receptors, and is currently used as an antiepileptic in dogs. Here we tested imepitoin for anxiolytic properties. In an in vitro model, imepitoin was capable of preventing the effect of cor...

詳細記述

保存先:
書誌詳細
主要な著者: Odilo Engel, Aleksandar Masic, Gary Landsberg, Melissa Brooks, Daniel S. Mills, Chris Rundfeldt
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2018-11-01
シリーズ:Frontiers in Pharmacology
主題:
dog
オンライン・アクセス:https://www.frontiersin.org/article/10.3389/fphar.2018.01225/full
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