Exploring the Parallel G-Quadruplex Nucleic Acid World: A Spectroscopic and Computational Investigation on the Binding of the c-myc Oncogene NHE III1 Region by the Phytochemical Polydatin

Trans-polydatin (tPD), the 3-β-D-glucoside of the well-known nutraceutical trans-resveratrol, is a natural polyphenol with documented anti-cancer, anti-inflammatory, cardioprotective, and immunoregulatory effects. Considering the anticancer activity of tPD, in this work, we aimed to explore the bind...

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Hauptverfasser: Francesca Greco, Domenica Musumeci, Nicola Borbone, Andrea Patrizia Falanga, Stefano D’Errico, Monica Terracciano, Ilaria Piccialli, Giovanni Nicola Roviello, Giorgia Oliviero
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-05-01
Schriftenreihe:Molecules
Schlagworte:
Pu22
G-quadruplex
c-myc
phytochemicals
circular dichroism
in silico simulations
Online Zugang:https://www.mdpi.com/1420-3049/27/9/2997
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