Gonadectomy in Mito-Ob mice revealed a sex-dimorphic relationship between prohibitin and sex steroids in adipose tissue biology and glucose homeostasis

Abstract Background Recently, we have developed a novel transgenic mouse model by overexpressing prohibitin (PHB) in adipocytes, which developed obesity due to upregulation of mitochondrial biogenesis in adipocytes, hence named “Mito-Ob.” Interestingly, only male Mito-Ob mice developed obesity-relat...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yang Xin Zi Xu, Sudharsana Rao Ande, Suresh Mishra
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2018-08-01
Edice:Biology of Sex Differences
Témata:
Prohibitin
Obesity
Adipocyte differentiation
17β-estradiol
Testosterone
Sex differences
On-line přístup:http://link.springer.com/article/10.1186/s13293-018-0196-4
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky